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2′-O-Methylation of Ribosomal RNA: Towards an Epitranscriptomic Control of Translation?

Ribosomal RNA (rRNA) undergoes post-transcriptional modification of over 200 nucleotides, predominantly 2′-O-methylation (2′-O-Me). 2′-O-Methylation protects RNA from hydrolysis and modifies RNA strand flexibility but does not contribute to Watson-Crick base pairing. The contribution of 2′-O-Me to t...

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Bibliografske podrobnosti
izdano v:Biomolecules
Main Authors: Monaco, Piero Lo, Marcel, Virginie, Diaz, Jean-Jacques, Catez, Frédéric
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316387/
https://ncbi.nlm.nih.gov/pubmed/30282949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom8040106
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