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A common molecular logic determines embryonic stem cell self‐renewal and reprogramming

During differentiation and reprogramming, new cell identities are generated by reconfiguration of gene regulatory networks. Here, we combined automated formal reasoning with experimentation to expose the logic of network activation during induction of naïve pluripotency. We find that a Boolean netwo...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Dunn, Sara‐Jane, Li, Meng Amy, Carbognin, Elena, Smith, Austin, Martello, Graziano
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316172/
https://ncbi.nlm.nih.gov/pubmed/30482756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100003
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