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BRCA1-Dependent Transcriptional Regulation: Implication in Tissue-Specific Tumor Suppression
Germ-line mutations in breast cancer susceptibility gene 1 (BRCA1) predominantly predispose women to breast and ovarian cancers. BRCA1 is best known for its functions in maintenance of genomic integrity including repairing DNA double-strand breaks through homologous recombination and suppressing DNA...
Guardat en:
| Publicat a: | Cancers (Basel) |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6316118/ https://ncbi.nlm.nih.gov/pubmed/30558184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10120513 |
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