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Fucoidan-Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Co-Targeting Tumor Hypoxia and Angiogenesis

Tumor hypoxia is a major mechanism of resistance to radiation therapy (RT), which is associated with poor prognosis in affected cancer patients. Various approaches to treat hypoxic and radioresistant cancers, including pancreatic cancer, have shown limited success. Fucoidan, a polysaccharide from br...

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Publicat a:Mar Drugs
Autors principals: Shin, Sung-Won, Jung, Wooju, Choi, Changhoon, Kim, Shin-Yeong, Son, Arang, Kim, Hakyoung, Lee, Nohyun, Park, Hee Chul
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316049/
https://ncbi.nlm.nih.gov/pubmed/30558324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16120510
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