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Fucoidan-Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Co-Targeting Tumor Hypoxia and Angiogenesis

Tumor hypoxia is a major mechanism of resistance to radiation therapy (RT), which is associated with poor prognosis in affected cancer patients. Various approaches to treat hypoxic and radioresistant cancers, including pancreatic cancer, have shown limited success. Fucoidan, a polysaccharide from br...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Shin, Sung-Won, Jung, Wooju, Choi, Changhoon, Kim, Shin-Yeong, Son, Arang, Kim, Hakyoung, Lee, Nohyun, Park, Hee Chul
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316049/
https://ncbi.nlm.nih.gov/pubmed/30558324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16120510
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