SIRT-3 Modulation by Resveratrol Improves Mitochondrial Oxidative Phosphorylation in Diabetic Heart through Deacetylation of TFAM

Background and Purpose: Mitochondrial dysfunction remains the crucial cause for many heart diseases including diabetic cardiomyopathy (DCM). Sirtuin-3 (SIRT-3) is a protein deacetylase localized in the mitochondria and regulates mitochondrial function. Being a noteworthy mitochondrial protein deacet...

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Vydáno v:Cells
Hlavní autoři: Bagul, Pankaj K., Katare, Parmeshwar B., Bugga, Paramesha, Dinda, Amit K., Banerjee, Sanjay K.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315986/
https://ncbi.nlm.nih.gov/pubmed/30487434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7120235
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