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Sirt1 and Sirt3 Activation Improved Cardiac Function of Diabetic Rats via Modulation of Mitochondrial Function

In the present study, we aimed to evaluate the effect of Sirt1, Sirt3 and combined activation in high fructose diet-induced insulin resistance rat heart and assessed the cardiac function focusing on mitochondrial health and function. We administered the Sirt1 activator; SRT1720 (5 mg/kg, i.p.), Sirt...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Paramesha, Bugga, Anwar, Mohammed Soheb, Meghwani, Himanshu, Maulik, Subir Kumar, Arava, Sudheer Kumar, Banerjee, Sanjay K
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996143/
https://ncbi.nlm.nih.gov/pubmed/33668369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10030338
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