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Knock-Down of a Novel snoRNA in Tetrahymena Reveals a Dual Role in 5.8S rRNA Processing and Generation of a 26S rRNA Fragment

In eukaryotes, 18S, 5.8S, and 28S rRNAs are transcribed as precursor molecules that undergo extensive modification and nucleolytic processing to form the mature rRNA species. Central in the process are the small nucleolar RNAs (snoRNAs). The majority of snoRNAs guide site specific chemical modificat...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Andersen, Kasper L., Nielsen, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315972/
https://ncbi.nlm.nih.gov/pubmed/30380771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom8040128
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