The conserved RNA exonuclease Rexo5 is required for 3′ end maturation of 28S rRNA, 5S rRNA, and snoRNAs

Non-coding RNA biogenesis in higher eukaryotes has not been fully characterized. Here, we studied the Drosophila melanogaster Rexo5 (CG8368) protein, a metazoan-specific member of the DEDDh 3′-5′ single-stranded RNA exonucleases, by genetic, biochemical, and RNA sequencing approaches. Rexo5 is requi...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Gerstberger, Stefanie, Meyer, Cindy, Benjamin-Hong, Sigi, Rodriguez, Joe, Briskin, Daniel, Bognanni, Claudia, Bogardus, Kimberly, Steller, Hermann, Tuschl, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662206/
https://ncbi.nlm.nih.gov/pubmed/29045842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.067
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