The Amino-Terminal Region of Hepatitis E Virus ORF1 Containing a Methyltransferase (Met) and a Papain-Like Cysteine Protease (PCP) Domain Counteracts Type I Interferon Response

Hepatitis E virus (HEV) is responsible for large waterborne epidemics of hepatitis in endemic countries and is an emerging zoonotic pathogen worldwide. In endemic regions, HEV-1 or HEV-2 genotypes are frequently associated with fulminant hepatitis in pregnant women, while with zoonotic HEV (HEV-3 an...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Bagdassarian, Eugénie, Doceul, Virginie, Pellerin, Marie, Demange, Antonin, Meyer, Léa, Jouvenet, Nolwenn, Pavio, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315852/
https://ncbi.nlm.nih.gov/pubmed/30567349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10120726
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