A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus

The Gn subcomponent of the Gn-Gc assembly that envelopes the human and animal pathogen, Rift Valley fever virus (RVFV), is a primary target of the neutralizing antibody response. To better understand the molecular basis for immune recognition, we raised a class of neutralizing monoclonal antibodies...

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Publicado no:Cell Rep
Main Authors: Allen, Elizabeth R., Krumm, Stefanie A., Raghwani, Jayna, Halldorsson, Steinar, Elliott, Angela, Graham, Victoria A., Koudriakova, Elina, Harlos, Karl, Wright, Daniel, Warimwe, George M., Brennan, Benjamin, Huiskonen, Juha T., Dowall, Stuart D., Elliott, Richard M., Pybus, Oliver G., Burton, Dennis R., Hewson, Roger, Doores, Katie J., Bowden, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315105/
https://ncbi.nlm.nih.gov/pubmed/30590046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.12.001
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