A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus

The Gn subcomponent of the Gn-Gc assembly that envelopes the human and animal pathogen, Rift Valley fever virus (RVFV), is a primary target of the neutralizing antibody response. To better understand the molecular basis for immune recognition, we raised a class of neutralizing monoclonal antibodies...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Allen, Elizabeth R., Krumm, Stefanie A., Raghwani, Jayna, Halldorsson, Steinar, Elliott, Angela, Graham, Victoria A., Koudriakova, Elina, Harlos, Karl, Wright, Daniel, Warimwe, George M., Brennan, Benjamin, Huiskonen, Juha T., Dowall, Stuart D., Elliott, Richard M., Pybus, Oliver G., Burton, Dennis R., Hewson, Roger, Doores, Katie J., Bowden, Thomas A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315105/
https://ncbi.nlm.nih.gov/pubmed/30590046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.12.001
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