SPA0355 prevents ovariectomy-induced bone loss in mice

Estrogen withdrawal in post-menopausal women leads to overactivation of osteoclasts, which contributes to the development of osteoporosis. Inflammatory cytokines are known as one of mechanisms of osteoclast activation after estrogen deficiency. SPA0355 is a thiourea derivative that has been investig...

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Veröffentlicht in:Korean J Physiol Pharmacol
Hauptverfasser: Kim, Sang Hoon, Zhang, Zhongkai, Moon, Young Jae, Park, Il Woon, Cho, Yong Gon, Jeon, Raok, Park, Byung-Hyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Physiological Society and The Korean Society of Pharmacology 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315098/
https://ncbi.nlm.nih.gov/pubmed/30627009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2019.23.1.47
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