The efficacy of SPA0355 in protecting β cells in isolated pancreatic islets and in a murine experimental model of type 1 diabetes

Cytokines activate several inflammatory signals that mediate β-cell destruction. We recently determined that SPA0355 is a strong anti-inflammatory compound, thus reporting its efficacy in protecting β cells from various insults. The effects of SPA0355 on β-cell survival were studied in RINm5F cells...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bae, Ui-Jin, Song, Mi-Young, Jang, Hyun-Young, Jin Gim, Hyo, Ryu, Jae-Ha, Lee, Sang-Myeong, Jeon, Raok, Park, Byung-Hyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849566/
https://ncbi.nlm.nih.gov/pubmed/24176948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.109
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