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A Novel Role for Co-Inhibitory Receptors/Checkpoint Proteins in the Immunopathology of Sepsis.

Co-inhibitory molecules, such as PD-1, CTLA-4, 2B4 and BTLA, are an important new family of mediators in the pathophysiology of severe bacterial and/or fungal infection, as well as the combined insults of shock and sepsis. Further, the expression of these molecules may serve as indicators of the imm...

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Dettagli Bibliografici
Pubblicato in:J Leukoc Biol
Autori principali: Fallon, Eleanor A., Biron-Girard, Bethany M., Chung, Chun-Shiang, Lomas-Neira, Joanne, Heffernan, Daithi S., Monaghan, Sean F., Ayala, Alfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314914/
https://ncbi.nlm.nih.gov/pubmed/29393983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.2MIR0917-377R
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