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Heterogeneous-Backbone Foldamer Mimics of a Computationally Designed, Disulfide-Rich Miniprotein

Disulfide-rich peptides have found widespread use in the development of bioactive agents; however, low proteolytic stability and difficulty exerting synthetic control over chain topology present barriers to applications in some systems. Here, we report a method that enables creation of artificial ba...

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Bibliographic Details
Published in:Chembiochem
Main Authors: Cabalteja, Chino C., Mihalko, Daniel S., Seth Horne, W.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314896/
https://ncbi.nlm.nih.gov/pubmed/30326175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800558
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