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Elevation of tumor mutation burden in ROS1-fusion lung adenocarcinoma resistant to crizotinib: A case report

RATIONALE: Although most of non-small cell lung cancer (NSCLC) patients with ROS1-fusions respond to crizotinb, acquired resistance eventually develop. The next-generations of ROS1 inhibitors have made some achievements, but the effects of immunotherapy have not been explored. PATIENT CONCERNS: A 44...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Yang, Tao, Xu, Rui, Yan, Bing, Li, Fang, Liu, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314749/
https://ncbi.nlm.nih.gov/pubmed/30593165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000013797
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