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Processive flow by biased polymerization mediates the slow axonal transport of actin

Classic pulse-chase studies have shown that actin is conveyed in slow axonal transport, but the mechanistic basis for this movement is unknown. Recently, we reported that axonal actin was surprisingly dynamic, with focal assembly/disassembly events (“actin hotspots”) and elongating polymers along th...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Chakrabarty, Nilaj, Dubey, Pankaj, Tang, Yong, Ganguly, Archan, Ladt, Kelsey, Leterrier, Christophe, Jung, Peter, Roy, Subhojit
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314539/
https://ncbi.nlm.nih.gov/pubmed/30401699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201711022
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