A dynamic formin-dependent deep F-actin network in axons

Although actin at neuronal growth cones is well-studied, much less is known about actin organization and dynamics along axon shafts and presynaptic boutons. Using probes that selectively label filamentous-actin (F-actin), we found focal “actin hotspots” along axons—spaced ∼3–4 µm apart—where actin u...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Ganguly, Archan, Tang, Yong, Wang, Lina, Ladt, Kelsey, Loi, Jonathan, Dargent, Bénédicte, Leterrier, Christophe, Roy, Subhojit
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523607/
https://ncbi.nlm.nih.gov/pubmed/26216902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506110
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