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Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum

Ovarian cancer preferentially metastasizes to the omentum, a fatty tissue characterized by immune structures called milky spots, but the cellular dynamics that direct this tropism are unknown. Here, we identified that neutrophil influx into the omentum is a prerequisite premetastatic step in orthoto...

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Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Lee, WonJae, Ko, Song Yi, Mohamed, Muhaned S., Kenny, Hilary A., Lengyel, Ernst, Naora, Honami
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314534/
https://ncbi.nlm.nih.gov/pubmed/30567719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181170
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