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Serum paraoxonase 1 activity is paradoxically maintained in nonalcoholic fatty liver disease despite low HDL cholesterol

Nonalcoholic fatty liver disease (NAFLD) is characterized by low HDL cholesterol, but the activity of the HDL-associated antioxidative enzyme paraoxonase-1 (PON-1) remains unclear. To determine the association of PON-1 with suspected NAFLD, we measured serum enzyme activity in 7,622 participants of...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: van den Berg, Eline H., Gruppen, Eke G., James, Richard W., Bakker, Stephan J. L., Dullaart, Robin P. F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314263/
https://ncbi.nlm.nih.gov/pubmed/30455362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P088997
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