Overexpression of acid ceramidase (ASAH1) protects retinal cells (ARPE19) from oxidative stress

Over 11 million people in the United States alone have some form of age-related macular degeneration (AMD). Oxidative stress, cell death, and the degeneration of retinal pigment epithelial (RPE) cells contribute to AMD pathology. Recent evidence suggests that ceramide (Cer), a cellular sphingolipid...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Sugano, Eriko, Edwards, Genea, Saha, Saikat, Wilmott, Lynda A., Grambergs, Richard C., Mondal, Koushik, Qi, Hui, Stiles, Megan, Tomita, Hiroshi, Mandal, Nawajes
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314257/
https://ncbi.nlm.nih.gov/pubmed/30413652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M082198
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