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CD47 protects synapses from excess microglia-mediated pruning during development
Microglia regulate synaptic circuit remodeling and phagocytose synaptic material in the healthy brain; however, the mechanisms directing microglia to engulf specific synapses and avoid others remain unknown. Here, we demonstrate that an innate immune signaling pathway protects synapses from inapprop...
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| Gepubliceerd in: | Neuron |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314207/ https://ncbi.nlm.nih.gov/pubmed/30308165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.09.017 |
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