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CD47 protects synapses from excess microglia-mediated pruning during development
Microglia regulate synaptic circuit remodeling and phagocytose synaptic material in the healthy brain; however, the mechanisms directing microglia to engulf specific synapses and avoid others remain unknown. Here, we demonstrate that an innate immune signaling pathway protects synapses from inapprop...
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| Publicado no: | Neuron |
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| Principais autores: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314207/ https://ncbi.nlm.nih.gov/pubmed/30308165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.09.017 |
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