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New insights on the role of microglia in synaptic pruning in health and disease
Recent genome-wide association studies implicate microglia in Alzheimer’s disease (AD) pathogenesis; however, their biological significance remains poorly understood. Synapse loss is a significant correlate of cognitive decline that serves as a critical hallmark of AD and other neurodegenerative dis...
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Publicado no: | Curr Opin Neurobiol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5479435/ https://ncbi.nlm.nih.gov/pubmed/26745839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2015.12.004 |
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