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New insights on the role of microglia in synaptic pruning in health and disease

Recent genome-wide association studies implicate microglia in Alzheimer’s disease (AD) pathogenesis; however, their biological significance remains poorly understood. Synapse loss is a significant correlate of cognitive decline that serves as a critical hallmark of AD and other neurodegenerative dis...

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Detalhes bibliográficos
Publicado no:Curr Opin Neurobiol
Main Authors: Hong, Soyon, Dissing-Olesen, Lasse, Stevens, Beth
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479435/
https://ncbi.nlm.nih.gov/pubmed/26745839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2015.12.004
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