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Defining TP53 pioneering capabilities with competitive nucleosome binding assays

Accurate gene expression requires the targeting of transcription factors (TFs) to regulatory sequences often occluded within nucleosomes. The ability to target a TF binding site (TFBS) within a nucleosome has been the defining characteristic for a special class of TFs known as pioneer factors. Recen...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Yu, Xinyang, Buck, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314159/
https://ncbi.nlm.nih.gov/pubmed/30409772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.234104.117
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