YbtT is a low-specificity type II thioesterase that maintains production of the metallophore yersiniabactin in pathogenic enterobacteria

Clinical isolates of Yersinia, Klebsiella, and Escherichia coli frequently secrete the small molecule metallophore yersiniabactin (Ybt), which passivates and scavenges transition metals during human infections. YbtT is encoded within the Ybt biosynthetic operon and is critical for full Ybt productio...

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Vydáno v:J Biol Chem
Hlavní autoři: Ohlemacher, Shannon I., Xu, Yiquan, Kober, Daniel L., Malik, Mahnoor, Nix, Jay C., Brett, Tom J., Henderson, Jeffrey P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314147/
https://ncbi.nlm.nih.gov/pubmed/30355735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005752
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