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Two clusters of residues contribute to the activity and substrate specificity of Fm1, a bifunctional oleate and linoleate desaturase of fungal origin

Polyunsaturated fatty acids (PUFAs) have important industrial, physiological, and nutritional properties. Plants use the sequential activities of FAD2 and FAD3 desaturases to convert 18:1Δ9 to the important PUFA 18:3Δ9,12,15, whereas the fungus Fusarium verticillioides 7600 uses the bifunctional des...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Cai, Yuanheng, Yu, Xiao-Hong, Liu, Qun, Liu, Chang-Jun, Shanklin, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314118/
https://ncbi.nlm.nih.gov/pubmed/30348899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005972
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