The aryl hydrocarbon receptor–cytochrome P450 1A1 pathway controls lipid accumulation and enhances the permissiveness for hepatitis C virus assembly

Viruses hijack and modify host cell functions to maximize viral proliferation. Hepatitis C virus (HCV) reorganizes host cell metabolism to produce specialized membrane structures and to modify organelles such as double-membrane vesicles and enlarged lipid droplets (LDs), thereby enabling virus repli...

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Vydáno v:J Biol Chem
Hlavní autoři: Ohashi, Hirofumi, Nishioka, Kazane, Nakajima, Syo, Kim, Sulyi, Suzuki, Ryosuke, Aizaki, Hideki, Fukasawa, Masayoshi, Kamisuki, Shinji, Sugawara, Fumio, Ohtani, Naoko, Muramatsu, Masamichi, Wakita, Takaji, Watashi, Koichi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314116/
https://ncbi.nlm.nih.gov/pubmed/30381393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005033
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