Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation

BACKGROUND: The widespread use of accessible peripheral tissues for epigenetic analyses has prompted increasing interest in the study of tissue-specific DNA methylation (DNAm) variation in human populations. To date, characterizations of inter-individual DNAm variability and DNAm concordance across...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Islam, Sumaiya A., Goodman, Sarah J., MacIsaac, Julia L., Obradović, Jelena, Barr, Ronald G., Boyce, W. Thomas, Kobor, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314079/
https://ncbi.nlm.nih.gov/pubmed/30602389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0245-6
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