DNA methylation signatures of chronic alcohol dependence in purified CD3(+) T-cells of patients undergoing alcohol treatment

Several studies have shown an association of alcohol dependence with DNA methylation (DNAm), suggesting that environmentally-induced changes on epigenomic variation may play an important role in alcohol dependence. In the present study, we analysed genome-wide DNAm profiles of purified CD3(+) T-cell...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Brückmann, Christof, Islam, Sumaiya A., MacIsaac, Julia L., Morin, Alexander M., Karle, Kathrin N., Di Santo, Adriana, Wüst, Richard, Lang, Immanuel, Batra, Anil, Kobor, Michael S., Nieratschker, Vanessa
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529570/
https://ncbi.nlm.nih.gov/pubmed/28747766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06847-z
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