Llwytho...
HDL Mimetic Peptide 4F Mitigates Aβ-Induced Inhibition of ApoE Secretion and Lipidation in Primary Astrocytes and Microglia
The apolipoprotein (apo) E ε4 allele is the primary genetic risk factor for late-onset Alzheimer’s disease (AD). ApoE in the brain is produced primarily by astrocytes; once secreted from these cells, apoE binds lipids and forms high-density lipoprotein (HDL)-like particles. Accumulation of amyloid-β...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Neurochem |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314045/ https://ncbi.nlm.nih.gov/pubmed/30028014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14554 |
| Tagiau: |
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