Ablation of soluble epoxide hydrolase reprogram white fat to beige-like fat through an increase in mitochondrial integrity, HO-1-adiponectin in vitro and in vivo()

We have shown that epoxyeicosatrienoic acids (EETs), specifically 11,12- and 14,15-EETs, reduce adipogenesis in human mesenchymal stem cells and mouse preadipocytes (3T-3L1). In this study, we explore the effects of soluble epoxide hydrolase (sEH) deletion on various aspects of adipocyte-function, i...

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Detalhes bibliográficos
Publicado no:Prostaglandins Other Lipid Mediat
Main Authors: Liu, Lu, Puri, Nitin, Raffaele, Marco, Schragenheim, Joseph, Singh, Shailendra P., Bradbury, J. Alyce, Bellner, Lars, Vanella, Luca, Zeldin, Darryl C., Cao, Jian, Abraham, Nader G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314013/
https://ncbi.nlm.nih.gov/pubmed/30041041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2018.07.004
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