Parathyroid Hormone Causes Endothelial Dysfunction by Inducing Mitochondrial ROS and Specific Oxidative Signal Transduction Modifications

Vitamin D deficiency contributes to cardiovascular risk (CVR), with hyperparathyroidism advocated as a putative mechanism. Indeed, mounting evidence supports the hypothesis that parathyroid hormone (PTH) impairs endothelial function, even though mechanisms are not fully elucidated. The present study...

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Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Gambardella, Jessica, De Rosa, Matteo, Sorriento, Daniela, Prevete, Nella, Fiordelisi, Antonella, Ciccarelli, Michele, Trimarco, Bruno, De Luca, Nicola, Iaccarino, Guido
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6313989/
https://ncbi.nlm.nih.gov/pubmed/30662585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9582319
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