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New Insights into Development of Transglutaminase 2 Inhibitors as Pharmaceutical Lead Compounds

Transglutaminase 2 (EC 2.3.2.13; TG2 or TGase 2) plays important roles in the pathogenesis of many diseases, including cancers, neurodegeneration, and inflammatory disorders. Under normal conditions, however, mice lacking TGase 2 exhibit no obvious abnormal phenotype. TGase 2 expression is induced b...

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Vydáno v:Med Sci (Basel)
Hlavní autor: Kim, Soo-Youl
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6313797/
https://ncbi.nlm.nih.gov/pubmed/30297644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medsci6040087
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