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Anti-inflammatory effects of the R2 peptide, an inhibitor of transglutaminase 2, in a mouse model of allergic asthma, induced by ovalbumin

BACKGROUND AND PURPOSE: Transglutaminase 2 (TGase 2) expression is increased in inflammatory diseases, and TGase 2 inhibitors block these increases. We examined whether the R2 peptide inhibited the expression of TGase 2 in a mouse model of inflammatory allergic asthma. EXPERIMENTAL APPROACH: C57BL/6...

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Detalhes bibliográficos
Main Authors: Kim, Dae Yong, Park, Bum Soo, Hong, Gwan Ui, Lee, Byung Jae, Park, Jung Won, Kim, Soo Youl, Ro, Jai Youl
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012417/
https://ncbi.nlm.nih.gov/pubmed/20840469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01033.x
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