Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD

Graft-versus-host disease (GVHD), a life-threatening complication after bone marrow transplantation (BMT), is induced by activation of alloreactive donor T cells. Our previous study demonstrated that transplantation of myeloid differentiation factor 88 (MyD88)-deficient knockout (KO) bone marrow (BM...

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Pubblicato in:Immune Netw
Autori principali: Lee, Young-Kwan, Ju, Ji-Min, Shon, Woo-Jeong, Oh, Sehwa, Min, Chang-Ki, Kang, Myung-Soo, Shin, Dong-Mi, Choi, Eun Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Association of Immunologists 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312895/
https://ncbi.nlm.nih.gov/pubmed/30619630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2018.18.e44
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