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Fast Magic-Angle-Spinning (19)F Spin Exchange NMR for Determining Nanometer (19)F–(19)F Distances in Proteins and Pharmaceutical Compounds

Internuclear distances measured using NMR provide crucial constraints of three-dimensional structures, but are often restricted to about 5 Å due to the weakness of nuclear-spin dipolar couplings. For studying macromolecular assemblies in biology and materials science, distance constraints beyond 1 n...

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Библиографические подробности
Опубликовано в: :J Phys Chem B
Главные авторы: Roos, Matthias, Wang, Tuo, Shcherbakov, Alexander A., Hong, Mei
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312665/
https://ncbi.nlm.nih.gov/pubmed/29486126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b00310
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