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Reciprocal regulation among TRPV1 channels and phosphoinositide 3-kinase in response to nerve growth factor
Although it has been known for over a decade that the inflammatory mediator NGF sensitizes pain-receptor neurons through increased trafficking of TRPV1 channels to the plasma membrane, the mechanism by which this occurs remains mysterious. NGF activates phosphoinositide 3-kinase (PI3K), the enzyme t...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6312403/ https://ncbi.nlm.nih.gov/pubmed/30560783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38869 |
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