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RAB10: an Alzheimer’s disease resilience locus and potential drug target

Alzheimer’s disease (AD) is mainly a late-onset neurodegenerative disorder. Substantial efforts have been made to solve the complex genetic architecture of AD as a means to identify therapeutic targets. Unfortunately, to date, no disease-altering therapeutics have been developed. As therapeutics are...

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Detalhes bibliográficos
Publicado no:Clin Interv Aging
Main Authors: Tavana, Justina P, Rosene, Matthew, Jensen, Nick O, Ridge, Perry G, Kauwe, John SK, Karch, Celeste M
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312396/
https://ncbi.nlm.nih.gov/pubmed/30643396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S159148
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