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Direct Asymmetric Alkylation of Ketones: Still Unconquered

The alkylation of ketones is taught at basic undergraduate level. In many cases this transformation leads to the formation of a new stereogenic center. However, the apparent simplicity of the transformation is belied by a number of problems. So much so, that a general method for the direct asymmetri...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Cano, Rafael, Zakarian, Armen, McGlacken, Gerard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312110/
https://ncbi.nlm.nih.gov/pubmed/28497890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201703079
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