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Optogenetic inhibition of Gα(q) protein signaling reduces calcium oscillation stochasticity
As fast terminators of G-protein coupled receptor (GPCR) signaling, regulators of G-protein signaling (RGS) serve critical roles in fine-tuning second messenger levels and, consequently, cellular responses to external stimuli. Here, we report the creation of an optogenetic RGS2 (opto-RGS2) that supp...
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| Опубликовано в: : | ACS Synth Biol |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6311707/ https://ncbi.nlm.nih.gov/pubmed/29792810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.8b00065 |
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