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Rapid and Modular Assembly of Click Substrates To Assay Enzyme Activity in the Newborn Screening of Lysosomal Storage Disorders

[Image: see text] Synthetic substrates play a pivotal role in the development of enzyme assays for medical diagnostics. However, the preparation of these chemical tools often requires multistep synthetic procedures complicating structural optimization and limiting versatility. In particular, substra...

詳細記述

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書誌詳細
出版年:ACS Cent Sci
主要な著者: Skrinjar, Philipp, Schwarz, Markus, Lexmüller, Stefan, Mechtler, Thomas P., Zeyda, Maximilian, Greber-Platzer, Susanne, Trometer, Joe, Kasper, David C., Mikula, Hannes
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2018
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311692/
https://ncbi.nlm.nih.gov/pubmed/30648152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.8b00668
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