Altered Synaptic Vesicle Release and Ca(2+) Influx at Single Presynaptic Terminals of Cortical Neurons in a Knock-in Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by the abnormal expansion of CAG repeats in the huntingtin (HTT) gene, which leads to progressive loss of neurons starting in the striatum and cortex. One possible mechanism for this selective loss of neurons in the early st...

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Bibliografski detalji
Izdano u:Front Mol Neurosci
Glavni autori: Chen, Sidong, Yu, Chenglong, Rong, Li, Li, Chun Hei, Qin, Xianan, Ryu, Hoon, Park, Hyokeun
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311661/
https://ncbi.nlm.nih.gov/pubmed/30618623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00478
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