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The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells

BACKGROUND: There are some limitations of standard chemotherapy for acute leukemia. Vincristine and doxorubicin are commonly used for acute leukemia, but they may induce serious side effects such as cardiomyopathy and neurotoxicity. Furthermore, chemotherapy resistance occurs more and more frequentl...

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Pubblicato in:Clin Epigenetics
Autori principali: Tu, Huang-Ju, Lin, Yi-Jyun, Chao, Min-Wu, Sung, Ting-Yi, Wu, Yi-Wen, Chen, Yi-Ying, Lin, Mei-Hsiang, Liou, Jing-Ping, Pan, Shiow-Lin, Yang, Chia-Ron
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310984/
https://ncbi.nlm.nih.gov/pubmed/30594243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0595-8
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