Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration

BACKGROUND: Neuronal cell loss contributes to the pathology of acute and chronic neurodegenerative diseases, including Alzheimer’s disease (AD). It remains crucial to identify molecular mechanisms sensitizing neurons to various insults and cell death. To date, the multifunctional, autophagy-related...

詳細記述

保存先:
書誌詳細
出版年:Mol Neurodegener
主要な著者: Bieri, Gregor, Lucin, Kurt M., O’Brien, Caitlin E., Zhang, Hui, Villeda, Saul A., Wyss-Coray, Tony
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2018
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310967/
https://ncbi.nlm.nih.gov/pubmed/30594228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0302-4
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