Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer’s disease

Phagocytosis controls CNS homeostasis by facilitating the removal of unwanted cellular debris. Accordingly, impairments in different receptors or proteins involved in phagocytosis result in enhanced inflammation and neurodegeneration. While various studies have identified extrinsic factors that modu...

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Xehetasun bibliografikoak
Egile Nagusiak: Lucin, Kurt M., O’Brien, Caitlin E., Bieri, Gregor, Czirr, Eva, Mosher, Kira I., Abbey, Rachelle J., Mastroeni, Diego F., Rogers, Joseph, Spencer, Brian, Masliah, Eliezer, Wyss-Coray, Tony
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779465/
https://ncbi.nlm.nih.gov/pubmed/24012002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.06.046
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