Rational targeting Cdc42 restrains Th2 cell differentiation and prevents allergic airway inflammation

BACKGROUND: Asthma is an allergic airway inflammation-driven disease that affects more than 300 million people worldwide. Targeted therapies for asthma are largely lacking. Although asthma symptoms can be prevented from worsening, asthma development can’t be prevented. Cdc42 GTPase has been shown to...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Exp Allergy
Main Authors: Yang, Jun-Qi, Kalim, Khalid W., Li, Yuan, Duan, Xin, Nguyen, Phuong, Khurana Hershey, Gurjit K., Kroner, John, Ruff, Brandy, Zhang, Li, Salomonis, Nathan, Rochman, Mark, Wen, Ting, Zheng, Yi, Guo, Fukun
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310654/
https://ncbi.nlm.nih.gov/pubmed/30307073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.13293
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