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Rational targeting Cdc42 restrains Th2 cell differentiation and prevents allergic airway inflammation

BACKGROUND: Asthma is an allergic airway inflammation-driven disease that affects more than 300 million people worldwide. Targeted therapies for asthma are largely lacking. Although asthma symptoms can be prevented from worsening, asthma development can’t be prevented. Cdc42 GTPase has been shown to...

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Detalhes bibliográficos
Publicado no:Clin Exp Allergy
Main Authors: Yang, Jun-Qi, Kalim, Khalid W., Li, Yuan, Duan, Xin, Nguyen, Phuong, Khurana Hershey, Gurjit K., Kroner, John, Ruff, Brandy, Zhang, Li, Salomonis, Nathan, Rochman, Mark, Wen, Ting, Zheng, Yi, Guo, Fukun
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310654/
https://ncbi.nlm.nih.gov/pubmed/30307073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.13293
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