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The Importance of mTOR Trafficking for Human Skeletal Muscle Translational Control

The mechanistic target of rapamycin (mTOR) is a central regulator of muscle protein synthesis, and its activation has long been attributed to its translocation to the lysosome. Here, we present a novel model of mTOR activation in skeletal muscle where the translocation of mTOR and the lysosome towar...

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Detalhes bibliográficos
Publicado no:Exerc Sport Sci Rev
Main Authors: Hodson, Nathan, Philp, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310455/
https://ncbi.nlm.nih.gov/pubmed/30334852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1249/JES.0000000000000173
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