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Synthesis of Hydrophobic Insulin-based Peptides Using a Helping-Hand Strategy
The introduction of solid-phase peptide synthesis in the 1960’s improved the chemical synthesis of both the A- and B-chains of insulin and insulin analogs. However, the subsequent elaboration of the synthetic peptides to generate active hormones continues to be difficult and complex due in part to t...
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| Publié dans: | Org Biomol Chem |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6310105/ https://ncbi.nlm.nih.gov/pubmed/29947407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob01212a |
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